Product Description

Common use
Alfacip (an analogue of vitamin D) contains active ingredient Alfacalcidol and administered to treat conditions with impairments of calcium metabolism caused by 1-α hydroxylation disorders such as when there is reduced renal function. The conditions treated by Alfacip are renal osteodystrophy, hyperparathyroidism (a disorder with parathyroid hormone deficiency, the substance required for the absorption of calcium and phosphorus), hypoparathyroidism, neonatal hypocalcaemia, nutritional and malabsorptive rickets and osteomalacia, pseudo-deficiency (D-dependent) rickets and osteomalacia, hypophosphataemic vitamin D resistant rickets and osteomalacia, osteoporosis.

Dosage and direction
Daily dose of Alfacip is 1 mcg/day. The dose should be reduced in the elderly, neonates and premature infants, children under 20 kg bodyweight.

Precautions
The patients treated by Alfacip should be regularly tested to avoid hypercalcaemia for plasma levels of calcium, parathyroid hormone, alkaline phosphatase, radiographic and histological investigations. The tests are needed especially for the patients with chronic renal failure because the decline of renal function may be aggravated by prolonged hypercalcaemia.

Contraindications
Patients with hypercalcaemia, metastatic calcification, hyperphosphataemia (except when occurring with hypoparathyroidism) or hypermagnesaemia, vitamin D toxicity or hypersensitivity to the vitamin D or its analogues cannot be treated by Alfacip.

Possible side effect
The following adverse reactions may occur: hypercalcemia, malaise, tiredness, weakness, nausea and vomiting, headache and dizziness, constipation or diarrhea, dry mouth, abdominal or gastrointestinal pain such as heartburn, heart palpitations, bone, muscle and joint pain.

Drug interaction
Long-term treatment with anticonvulsants, including phenytoin, may change vitamin D and calcium metabolism. This results in metabolic bone disease and hypocalcaemia and even seizures. Monitoring of calcium levels in the patients on antiepileptic drugs is required.

Missed dose
If you forgot to take your dose in time, please do it as soon as you remember. But do not take if it is too late or almost time for your next dose. Do not increase your recommended dose. Take your doses at about the same time each day to avoid missing a dose.

Overdose
Signs of Alfacip overdose may be the following: high fever, high blood pressure, irregular heartbeat, stomach pain (severe).

Storage
Store at room temperature between 59-77 F (15-25 C) away from light and moisture, kids and pets. Do not use after expiration term.

Disclaimer
We provide only general information about medications which does not cover all directions, possible drug integrations,trex theory include nausea, vomiting, diarrhea and headache. Some patients experience agitation, dizziness, confusion edema, sore throat, constipation abdominal pain, rash, weakness and kidney problems. The most severe adverse reactions include seizures, coma, leucopenia, (low white blood count), loss of appetite, fatigue, and hepatitis.
Another very serious side effect occurs suddenly and can lead to death is anaphylaxis. Anaphylaxis symptoms are itchy rash, throat swelling and low blood pressure.
Valtrex may interact with other medicines such as cimetidine and probenecid. Because Vaktrex may react with other medications make sure you physician is aware of all medicines you take including herbals, over the counter medications and dietary supplement. He/she should also be aware if you smoke, drink alcohol, or use illegal drugs.
If your symptoms do not improve when taking this medication after a week’s time notify you physician. This medication works best if it is started within 72 of the onset of symptoms. These symptoms which are a signal of the infections are tingling, itching and/or pain in the affected area
Genital herpes can still be spread even when you do not have symptoms of the infection. It is best to use a condom when having sex with a person with a history of genital herpes.
You should also remember to drink plenty of liquids so you do not become dehydrated.

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