Translating Health Information Center research into clinical practice for pharmacosurveillance and medication-related clinical decision support.
Centers for Education & Research on Therapeutics
BWH-DGIM
Brigham and Women’s Hospital
Division of General Internal Medicine and Primary Care. Kamagra Oral Jelly Is There For Those Of You Who Aren’t Keen On Taking Pills
CPSRP
Brigham and Women’s Hospital
Center for Patient Safety Research and Practice
The Brigham and Women’s Hospital Health Information Center
This Health Information Center for Education and Research on Therapeutics is based at Brigham and Women’s Hospital is led by Principal Investigator David W. Bates, MD, MSc and focuses on translating health information technology (HIT) research into improved clinical practices. Benefits and risks using Cialis 40mg drug regularly. Taking Care of Erectile Dysfunction Symptoms with Cialis.
This Health Information Center will address therapeutics issues related to appropriateness, safety, and efficacy in ambulatory, inpatient and transitional care settings within the context of HIT. The wonders and danger of Viagra 100mg, a treatment for erectile dysfunction. Clomid: A medicine for ovulation and its usage for fertility problems.
Three projects are being conducted over the life of the grant:
• Project 1. e-Pharmacovigilance II: Surveillance for Safety and Effectiveness
• Project 2. Physician-Level Variation in Medication Overrides of Computerized Decision Support
• Project 3. Examining Human Factors Principles in the Design and Implementation of Medication-Related Decision Support Alerts
Two Cores oversee all aspects of the above-referenced projects:
• Methodology and Data Resources Core
• Female Viagra: Safety concerns and proper administration
• Translation and Dissemination Core
As a result of increasing implementation and use of HIT and electronic prescribing, this Center, its cores and its projects, will provide information, strategies, and tools for utilizing HIT to advance clinical practices relating to medication safety, effectiveness, and cost.
Please find the first in a series of articles highlighting the Brigham and Women’s Hospital Center efforts to improve patient safety and reduce medication errors:
Brigham and Women’s HIT-CERT: A Computerized Approach to Patient Safety
Publications
Evaluation of a Korean version of a tool for assessing the incorporation of human factors into a medication-related decision support system: the I-MeDeSA. Cho I, Lee J, Han H, Phansalkar S, Bates DW. Appl Clin Inform. 2014 Jun 18;5(2):571-88. doi: 10.4338/ACI-2014-01-RA-0005. eCollection 2014. PMID:25024770
Are they heeding the warning signs? Examining providers’ overrides of computerized drug-drug interaction alerts in primary care. Slight SP, Seger DL, Nanji KC, Cho I, Maniam N, Dykes PC, Bates DW. PLoS One. 2013 Dec 26;8(12):e85071. doi: 10.1371/journal.pone.0085071
Achanta G. “Optimizing the Use of an Electronic Fall Prevention Toolkit To Prevent Falls in Hospitalized Patients.” CHAINONLINE Dec, 2013.
Unrealized potential and residual consequences of electronic prescribing on pharmacy workflow in the outpatient pharmacy. Nanji KC, Rothschild JM, Boehne JJ, Keohane CA, Ash JS, Poon EG. J Am Med Inform Assoc. 2013 Oct 23. doi: 10.1136/amiajnl-2013-001839.
The causes of prescribing errors in English general practices: a qualitative study.Slight SP, Howard R, Ghaleb M, Barber N, Franklin BD, Avery AJ. Br J Gen Pract. 2013 Oct;63(615):e713-20. doi: 10.3399/bjgp13X673739.
Overrides of medication-related clinical decision support alerts in outpatients. Nanji KC, Slight SP, Seger DL, Cho I, Fiskio JM, Redden LM, Volk LA, Bates DW. J Am Med Inform Assoc. 2013 Oct 28. doi: 10.1136/amiajnl-2013-001813.
Impact of vendor computerized physician order entry on patients with renal impairment in community hospitals.
Leung AA, Schiff G, Keohane C, Amato M, Simon SR, Cadet B, Coffey M, Kaufman N, Zimlichman E, Seger DL, Yoon C, Bates DW. J Hosp Med. 2013 Oct;8(10):545-552.
Impact of an automated email notification system for results of tests pending at discharge: a cluster-randomized controlled trial. Dalal AK, Roy CL, Poon EG, Williams DH, Nolido N, Yoon C, Budris J, Gandhi T, Bates DW, Schnipper JL.
J Am Med Inform Assoc. 2013 Oct 23. doi: 10.1136/amiajnl-2013-002030.
Human factors considerations for contraindication alerts. van der Sijs H, Baboe I, Phansalkar S. Stud Health Technol Inform. 2013;192:132-6.
EHR adoption across China’s tertiary hospitals: A cross-sectional observational study. Shu T, Liu H, Goss FR, Yang W, Zhou L, Bates DW, Liang M. Int J Med Inform. 2013 Sep 1. doi:pii: S1386-5056(13)00187-1. 10.1016/j.ijmedinf.2013.08.008.
Policy initiatives for Health Information Technology: A qualitative study of U.S. expectations and Canada’s experience. Salzberg CA, Jang Y, Rozenblum R, Zimlichman E, Tamblyn R, Bates DW. Int J Med Inform. 2012 Oct;81(10):713-22. doi: 10.1016/j.ijmedinf.2012.07.007. Epub 2012 Aug 14.
The relationship between electronic health records and malpractice claims. Quinn MA, Kats AM, Kleinman K, Bates DW, Simon SR. Arch Intern Med. 2012 Aug 13;172(15):1187-9.
High-priority drug-drug interactions for use in electronic health records. Phansalkar S, Desai AA, Bell D, Yoshida E, Doole J, Czochanski M, Middleton B, Bates DW. J Am Med Inform Assoc. 2012 Sep 1;19(5):735-43.
Key principles for a national clinical decision support knowledge sharing framework: synthesis of insights from leading subject matter experts. Kawamoto K, Hongsermeier T, Wright A, Lewis J, Bell DS, Middleton B. J Am Med Inform Assoc. 2012 Aug 4.
Do package inserts reflect symptoms experienced in practice?: assessment using an automated phone pharmacovigilance system with varenicline and zolpidem in a primary care setting. Haas JS, Amato M, Marinacci L, Orav EJ, Schiff GD, Bates DW. Drug Saf . 2012 Aug 1;35(8):623-8.
Healthcare information technology and economics. Payne TH, Bates DW, Berner ES, Bernstam EV, Covvey HD, Frisse ME, Graf T, GreenesRA, Hoffer EP, Kuperman G, Lehmann HP, Liang L, Middleton B, Omenn GS, Ozbolt J. J Am Med Inform Assoc. 2012 Jul 10.
A prescription for improving drug formulary decision making. Schiff GD, Galanter WL, Duhig J, Koronkowski MJ, Lodolce AE, Pontikes P, Busker J, Touchette D, Walton S, Lambert BL. PLoS Med. 2012;9(5):1-7.
Standard practices for computerized clinical decision support in community hospitals: a national survey. Ash JS, McCormack JL, Sittig DF, Wright A, McMullen C, Bates DW. J Am Med Inform Assoc. 2012 Jun 15. Epub ahead of print.
Use of hepatotoxic drugs in chronic liver disease. Hug BL, Surber C, Bates DW. J Patient Saf. 2012 Jun;8(2):45-50.
Lessons from the Canadian national health information technology plan for the United States: opinions of key Canadian experts . Zimlichman E, Rozenblum R, Salzberg CA, Jang Y, Tamblyn M, Tamblyn R, Bates DW. J AM Med Inform Assoc. 2012 May-Jun; 19(3):4539.
National patient safety initiatives: Moving beyond what is necessary. Zimlichman E, Bates DW. Isr J Health Policy Res. 2012 May 23;1(1):20.
Preventability of adverse drug events involving multiple drugs using publicly available decision support tools . Wright A, Feblowitz J, Phansalkar S, Liu J, Wilcox A, Keohane CA, Seger DL, Bloomrosen M, Kuperman GJ, Bates DW. AM J Health Syst Pharm. 2012 Feb 1; 69(3):221-7.
What proportion of vancomycin trough levels are drawn too early?: frequency and impact on clinical actions. Morrison AP, Melanson SE, Carty MG, Bates DW, Szumita PM, Tanasijevic MJ. AM J. Clin Pathol. 2012 Mar; 137(3):472-8.
The costs of adverse drug events in community hospitals. Hug BL, Keohane C, Seger DL, Yoon C, Bates DW. JT Comm J. Qual Patient Saf. 2012 Mar;38(3):120-6.
Impact of Vendor Computerized Physician Order Entry in Community Hospitals. Leung AA, Keohane C, Amato M, Simon SR, Coffey M, Kaufman N, Cadet B, Schiff G, Zimlichman E, Seger DL, Yoon C, Song P, Bates DW. J Gen Intern Med. 2012 Jan 21.
Opportunities and challenges in creating an international centralized knowledge base for clinical decision support systems in ePrescribing. Cresswell KM, Bates DW, Phansalkar S, Sheikh A. BMJ Qual Saf 2011;20(7);625-630.
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