Cialis or Tadalafil is film-coated pill which is used for treatment of erectile dysfunction. Cialis belongs into the group of drugs called phosphodiesterase type 5 inhibitor (PDE5 inhibitor), he is selective, reversible inhibitor. Normally, physiologically, during the sexual stimulation, corpus cavernosum of male reproductive organ release NO (nitric oxide) which activates cascade of enzymes, which as result have increase of blood circulation in corpus cavernosum blood vessels, and relaxation of corpus cavernosum muscles. And all of that leads to erection, which is the main goal. Other uses of Cialis are not approved yet officially, but scientists believe that it can be used in treatment of high blood pressure in the lungs (also called pulmonary hypertension). Also it can be used in the treatment of benign prostatic hyperplasia-BPH, because it releases prostate and bladder muscles. This drug does not protect you from sexually transmitted diseases, although very important, that’s another theme for thinking about, but it’s related to topic of active sexual life.
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Tadalafil have very good oral absorption, and his maximally concentration in blood is within 2 hours, and effects occur even till next 36 hours from the time when you take this pill. But without sexual stimulation, there is no effect at all. This drug should be taken about half hour, to 12 hours before sexual intercourse. It is allowed to take only one dose per day. That does should be 20mg of Cialis, once per day, nowise more, because it could be very dangerous. You should take this pill with food, and water or without, depending on your consultation with experts. It can be taken every day, if male want to have regular sexual life, but also can be taken only before sexual intercourse that you are planning at that exact time, as I’ve mentioned, 30 minutes before planned action. Women and children should not take this preparation, logically.
Cialis has its metabolism in the liver, and its excretion is over gastrointestinal system (about 60 percent), and also by urinary tract (about 35 percent).
Before use, you should have consultation with your medical doctor, or with pharmacist, and carefully read patient information leaflet that goes with package of pills. Side effects are much more common if male have some hearth disease, or any other chronically disease (liver, renal, etc.), especially if takes therapy which contains vasodilator drugs.
Side effects
Side effects are headache, and dyspepsia, but they appear very rarely. In the case of appearing much more dangerous side effects such as chest pain, dizziness, or nausea, during, especially during the sexual intercourse, patient should immediately ask for medical help.
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I am self employed. General Practitioner in Melbourne, VIC. My special interest: male reproductive system.