Cialis is known as a competitor of Viagra, commonly also known as tadalafil, is a medication that is used to treat erectile dysfunction in males and also pulmonary arterial hypertension. as of now Cialis has not shown to treat sexual dysfunction in women. Cialis operates by inhibiting specific enzymes that promote degradation of cyclic guanosine monophosphate. It primarily operates as the mechanism of action in intracellular protein kinases in response to binding of membrane impermeable peptide hormones. This causes relaxation of smooth muscle tissues, primarily in the penis which leads to vasodilation and increased blood flow.
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Cialis was initially discovered by Pfizer scientists after sildenafil also known as viagra was found, and other research of PDE5 inhibitors were done. The company Glaxo Wellcome had done clinical trials on medication for joint pain and found that it also helped with erectile disfunction and entered a venture to have it commercially sold as a treatment for erectile disfunction. The FDA in approved it in 2003. The primary use for treatment with Cialis is for sexual dysfunction, categorized as the inability to sustain a satisfactory erection to complete intercourse. It is also been used to treat pulmonary hypertension and antidepressant Associated sexual dysfunction. Side effects of using Cialis include headaches and heartburn as well as flushed skin. Also included in the side effects of prolonged erections which can lead to damage to the penis. Also Cialis is not recommended for people taking nitrates such as nitroglycerin as this may result in a severe drop in blood pressure which may lead to death. Cialis has thrived in many countries due to the patent of it’s name cousin, Viagra, wearing out. This has allowed many companies to capitalize on this and produce a cheaper version, which allows it to be available to more people by widening it’s user base. Cialis’ popularity with young adults has increased in the past few years, the Drug’s association with erectile dysfunction treatment has led to its common recreational use.
Many people believe that the drug will increase their libido or improve their sexual performance. although in those not suffering from erectile dysfunction it did reduce the post ejaculatory refractory time there was also a very significant placebo effect in the control group.Other Studies have documented that when using Cialis professional athletes have noted that the opening of their blood vessels in which their muscles and in turn believe it enhances their performance ability. In Australia, Cialis is still widely bought along with its competitors such as Viagra, for erectile dysfunction treatment. It is commonly sold in online pharmacies, and over the counter.
Much like in other countries such as the United States, Canada, and the European Union, the use of Cialis has increased due to being a slightly different drug, which may help those that have issues with other PDE5 inhibitors. Cialis also has a improved strength version which is designed to last even longer than it’s competitors called Cialis Super-Active and has been very popular as a prescription for treating ED in Australia.
I am self employed. General Practitioner in Melbourne, VIC. My special interest: male reproductive system.