HOW TO BUY GENERIC CIALIS

Cialis is a film-coated, yellow almond-shaped medication with the Active Pharmaceutical Ingredient tadalafil.

It comes in different strengths:

• Cialis 2.5 tablets
• Cialis 5mg tablets
• Cialis 10mg tablets
• Cialis 20mg tablets

 INDICATIONS
This medication is indicated for various conditions. These includes:

§ Erectile dysfunction

§ Benign prostatic hyperplasia
§ Combination of erectile dysfunction and benign prostatic hyperplasia.
§ And pulmonary arterial hypertension

The Active Pharmaceutical Ingredient is Tadalafil.

Buy Generic Cialis 20mg in Australia

 MODE OF ACTION

Tadalafil is a phosphodiesterase type 5 inhibitor. The inhibition of this enzyme mediates the synthesis of nitric oxide from the endothelial cells and nerve endings. This then initiates the synthesis of a second messenger, the cyclic guanosine monophosphate(cGMP) in the smooth muscle cells.

In cases of erectile dysfunction, the cGMP then stimulates the relaxation of smooth muscles and thus aiding an increased blood flow to the corpus cavernosum. This way, it promotes the erectile function. However, the synthesis of the nitric oxide is dependent on sexual stimulation and thus cialis tablets have no effect in absence of a direct sexual stimulation unto the penis.

In patients with the benign prostatic hyperplasia, it helps the relaxation of the muscles within and around the prostate glands thus enhancing the free flow of urine.

For the pulmonary arterial hypertension, it increases the lumen of the pulmonary vascular thus causing the vasodilation of the artery and lowering the arterial blood pressure. It also inhibits the vascular remodeling and thus lowers its resistance

Tadalafil has a relatively long half-life of approximately 17.5 hours.

 DOSAGE.
§ For the erectile dysfunction, the starting dose is 10mg taken before sexual activity when need be. The dosage shouldn’t exceed one tablet daily. The dosage maybe decreased to 5mg or increased to 20mg depending on its efficacy and the individual’s tolerance of the drug.
§ For the pulmonary arterial hypertension, 40mg is recommended as a once daily dosage to improve the patient’s exercise ability.
§ For the benign prostatic hyperplasia and the prostatic hyperplasia with the erectile dysfunction, 5mg taken once daily is recommended

 DRUG INTERACTIONS

Ornagic nitrates such as amyl nitrate should not be taken for at least 48 hours after the last dosage of tadalafil. Tadalafil causes briefly low blood pressure and thus its use in the same timeframe with the organic nitrates may cause a life threatening hypotension

On the other hand, tadalafil is metabolised by the hepatic CYP3A4 enzyme system. Co-administration of cialis with the other drugs known to induce this enzymatic system i.e. ( acetaminophen, cyclosporin, erythromycin ) may shorten its lifetime and thus lower the efficacy.

SIDE EFFECTS

§ The main common side effects associated with the intake of cialis includes; stomach discomforts, headache, indigestion, acid reflux, burping, back pain, flushing, muscle aches, and runny or stuffy nose. These symptoms disappear after 48 hour.

 CAUTION

Seek medical advise before taking cialis if you have any of the following conditions:
§ Stomach ulcers
§ Any kidney or liver disease
§ If you have ever experienced a heart attack
§ Retinitis pigmentosa
§ Any heart disease
§ High or low blood pressure
§ Hemophilia or any other bleeding disorder
§ Leukemia, sickle cell anemia or multiple myeloma.

 A WORD OF ADVICE!

It’s is not advisable to split the tablets. It is advisable for one to buy the right strength of the drug i.e. the 5mg instead of buying the 10mg and dividing it into two. This is because the drug is usually enteric coated to lower the effects of gastrointestinal irritation.

HOW TO BUY CIALIS:

Cialis is available as a prescription only drug. Anyone with the above mentioned conditions should seek medical advice before opting to take cialis medication. This means that you will have to present a prescription of the same from a registered medical practitioner to the pharmacy for you to buy the drug. This drug is readily available in almost all the drug stores and pharmacies.

 BRAND AND GENERIC MEDICATION.

Be warned of counterfeit! Cialis is the only brand of tadalafil indicated for erectile dysfunction in the market. There are yet no generics for the drug so far!
The only other drug with the tadalafil as the Active Pharmaceutical Ingredient is adcirca which is also a brand and only indicated specifically for the pulmonary arterial hypertension.

PRICES ONLINE

The prices for cialis generally differ depending on the strength i.e. 5mg, 10mg, 20mg etc.
The price also differs in line with different sellers online. For instant, the edonlinestore.net offers the cialis 20mg × 5 pills at $202, cialis 20mg × 10 pills at $395, Cialis 20mg × 20 pills at $777 and Cialis 20mg × 30 pill at $1147.
It’s advisable to compare different prices with different seller online.