Nolvadex is the name of a medication used for the treatment of breast cancer that has spread to other parts of the body. A condition known as metastasic breast cancer. The generic name is Tamoxifen citrate and it is used in patients with breast cancer after surgery and radiation therapy. It is also used in patient with high risk of breast cancer.
Tamoxifen citrate (Nolvadex), acts by slowing or stopping the growth of cancer cells that are present in the body. It stops the original breast cancer from coming back and helps in the prevention of a new breast cancer in the opposite breast. It is also very useful to prevent a breast cancer in women with a high risk of it.
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Hormone therapy and Breast cancer: Progesterone and estrogen can promote the growth of some breast cancers called hormone sensitive breast cancers. These hormone sensitive breast cancer cells contain proteins known as hormone receptors that get activated if hormones bind to them. The result is stimulation of cell growth. Doctors take samples of tumor tissue and analyze them. If the tissue contains estrogen receptors, the cancer is classified as receptor positive (ER positive), estrogen sensitive or estrogen responsive. About a seventy percent of breast cancers are ER positive. In these cases, doctors may use hormone therapy to slow the growth of the tumor by blocking the body´s ability to produce hormones or interfering with hormone action. Tamoxifen binds to estrogen receptors, preventing estrogen from binding.
Nolvadex or Tamoxifen comes as a tablet to take by mouth. The medication is usually taken once or twice a day, and it doesn´t matter if taken with or without food. What is really important is to take it around the same time each day. The patient must follow the indications of her doctor and take tamoxifen exactly as directed and never take less or more than prescribed. The tablets should not be split, chewed or crushed, and must be swallowed with water or any other non alcoholic beverage. Sometimes the patient needs to take the tamoxifen for five years, but it must be always the doctor who decides the length of the treatment.
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Recommendations for patients on Nolvadex: It is important to have gynecological check-ups, breast exams and a mammogram or/and breast ultrasound, This way you can be sure that your breast and uterus are okay. Novaldex can cause side effects, so it is important to pay attention to your body. The most frequent side effect is hot flashes and it is not a serious issue. There are other side effects like vaginal bleeding or bloody discharges, changes in your menstruation or pelvic pain that are not so frequent, but must be checked by your doctor. There is a list of infrequent side effects that your doctor can give to you so you can be alert in case of having them.
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